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glb-6 Globin-like protein 6 [ Caenorhabditis elegans ]

Gene ID: 182780, updated on 2-Nov-2024

Summary

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Official Symbol
glb-6
Official Full Name
Globin-like protein 6
Primary source
WormBase:WBGene00015969
Locus tag
CELE_C18C4.9
See related
AllianceGenome:WB:WBGene00015969
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Is expressed in neurons and somatic nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See glb-6 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (5568184..5570533, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene GRIP domain-containing protein;Golgin-84 Neighboring gene Globin domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Yoon J, et al. Biochemistry, 2010 Jul 13. PMID 20518498, Free PMC Article
  2. Computational evidence support the hypothesis of neuroglobin also acting as an electron transfer species. Paltrinieri L, et al. J Biol Inorg Chem, 2017 Jun. PMID 28378164
  3. Globins in Caenorhabditis elegans. Tilleman L, et al. IUBMB Life, 2011 Mar. PMID 21445847
  4. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. Hoogewijs D, et al. BMC Genomics, 2007 Oct 4. PMID 17916248, Free PMC Article
  5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
NOT enables carbon monoxide binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables heme binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables nitric oxide binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxygen binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxygen binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxygen binding IEA
Inferred from Electronic Annotation
more info
  
enables oxygen carrier activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxygen carrier activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in oxygen transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in oxygen transport IEA
Inferred from Electronic Annotation
more info
  
involved_in response to hypoxia IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Globin-like protein 6
NP_504469.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5568184..5570533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072068.6 → NP_504469.1  Globin-like protein 6 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504469.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18086
    Conserved Domains (1) summary
    cd01040
    Location:205 → 342
    Mb_like; myoglobin_like; M family globin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18086.2

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