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C07H6.2 E3 ubiquitin-protein ligase PPP1R11 [ Caenorhabditis elegans ]

Gene ID: 182382, updated on 9-Dec-2024

Summary

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Official Symbol
C07H6.2
Official Full Name
E3 ubiquitin-protein ligase PPP1R11
Primary source
WormBase:WBGene00015579
Locus tag
CELE_C07H6.2
See related
AllianceGenome:WB:WBGene00015579
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein phosphatase 1 binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be active in nucleus. Is expressed in intestine and pharynx. Orthologous to human PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C07H6.2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_003281.10 (7521009..7521332)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein CLASP-1 Neighboring gene Telomere length regulation protein clk-2 Neighboring gene RRM domain-containing protein Neighboring gene DNA ligase IV Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein phosphatase 1 binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
E3 ubiquitin-protein ligase PPP1R11
NP_498652.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7521009..7521332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066251.5 → NP_498652.1  E3 ubiquitin-protein ligase PPP1R11 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498652.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95YE7
    Conserved Domains (1) summary
    pfam07491
    Location:28 → 75
    PPI_Ypi1; Protein phosphatase inhibitor
Nucleotide Protein
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