emre-1 Essential MCU regulator, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: emre-1
Official Full Name: Essential MCU regulator, mitochondrial
Primary source: WormBase:WBGene00008980
Locus tag: CELE_F20D1.10
See related: AllianceGenome:WB:WBGene00008980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in mitochondrial calcium ion homeostasis and mitochondrial calcium ion transmembrane transport. Located in mitochondrion. Is expressed in body wall musculature and nervous system. Orthologous to human SMDT1 (single-pass membrane protein with aspartate rich tail 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See emre-1 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 2

Sequence:: Chromosome: X; NC_003284.9 (14979688..14980140)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F20D1.3 (e-PCR)
- UniSTS:307510

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in calcium import into the mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in calcium import into the mitochondrion	IEA Inferred from Electronic Annotation more info
involved_in calcium ion transport	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial calcium ion homeostasis	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial calcium ion homeostasis	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial calcium ion homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial calcium ion transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of uniplex complex	IBA Inferred from Biological aspect of Ancestor more info
part_of uniplex complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Essential MCU regulator, mitochondrial

NP_510487.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

14979688..14980140

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_078086.7 → NP_510487.1 Essential MCU regulator, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_510487.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9U3I4

Conserved Domains (1) summary

pfam10161
Location:32 → 83

DDDD; Putative mitochondrial precursor protein