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tsp-8 Tetraspanin [ Caenorhabditis elegans ]

Gene ID: 181567, updated on 4-Jan-2025

Summary

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Official Symbol
tsp-8
Official Full Name
Tetraspanin
Primary source
WormBase:WBGene00006634
Locus tag
CELE_F33C8.3
See related
AllianceGenome:WB:WBGene00006634
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in body wall musculature. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See tsp-8 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (14726626..14729503, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene CUB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF38 domain-containing protein Neighboring gene KIF-binding protein Neighboring gene MFS domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Tetraspanin
NP_510445.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    14726626..14729503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078044.7 → NP_510445.1  Tetraspanin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510445.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19983
    Conserved Domains (3) summary
    cd03127
    Location:108 → 243
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:8 → 276
    Tetraspannin; Tetraspanin family
    cl00275
    Location:13 → 108
    Heme_Cu_Oxidase_I; Heme-copper oxidase subunit I. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane. The superfamily is ...
Nucleotide Protein
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