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nhr-71 Nuclear hormone receptor family member nhr-71 [ Caenorhabditis elegans ]

Gene ID: 181491, updated on 9-Dec-2024

Summary

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Official Symbol
nhr-71
Official Full Name
Nuclear hormone receptor family member nhr-71
Primary source
WormBase:WBGene00003661
Locus tag
CELE_K11E4.5
See related
AllianceGenome:WB:WBGene00003661
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in intestine; pharyngeal neurons; seam cell; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-71 in Genome Data Viewer
Location:
chromosome: X
Exon count:
10
Sequence:
Chromosome: X; NC_003284.9 (13747315..13751797)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene SH3 domain-containing protein Neighboring gene tRNA-Lys Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Lys Neighboring gene Association with the SNF1 complex (ASC) domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations. Ratnappan R, et al. Worm, 2016 Jan-Mar. PMID 27073739, Free PMC Article
  2. Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. Pathare PP, et al. PLoS Genet, 2012. PMID 22511885, Free PMC Article
  3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nuclear hormone receptor family member nhr-71
NP_001024787.1
  • Confirmed by transcript evidence
NP_001024788.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13747315..13751797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029616.6 → NP_001024787.1  Nuclear hormone receptor family member nhr-71 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024787.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EEW8, Q9GTD4, Q9GTD5, Q9TVX9
    Conserved Domains (2) summary
    cd06960
    Location:10 → 85
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
    pfam00104
    Location:222 → 428
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor

  2. NM_001029617.5 → NP_001024788.1  Nuclear hormone receptor family member nhr-71 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024788.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EEW8, Q9GTD4, Q9GTD5, Q9TVX9
    Conserved Domains (2) summary
    cd06960
    Location:10 → 88
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
    pfam00104
    Location:225 → 431
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor
Nucleotide Protein
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