C29F7.3 UMP-CMP kinase 1 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: C29F7.3
Official Full Name: UMP-CMP kinase 1
Primary source: WormBase:WBGene00007812
Locus tag: CELE_C29F7.3
See related: AllianceGenome:WB:WBGene00007812
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables UMP kinase activity. Involved in UDP biosynthetic process. Predicted to be active in cytoplasm and nucleus. Is expressed in hypodermis; intestine; and pharynx. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human CMPK1 (cytidine/uridine monophosphate kinase 1). [provided by Alliance of Genome Resources, Jan 2025]
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Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables (d)CMP kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables (d)CMP kinase activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables CMP kinase activity	IEA Inferred from Electronic Annotation more info
enables UMP kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UMP kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables UMP kinase activity	IEA Inferred from Electronic Annotation more info
enables UMP/dUMP kinase activity	IEA Inferred from Electronic Annotation more info
enables dCMP kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleobase-containing compound kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 'de novo' pyrimidine nucleobase biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in CDP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in UDP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in UDP biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in nucleobase-containing compound metabolic process	IEA Inferred from Electronic Annotation more info
involved_in nucleoside monophosphate phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in pyrimidine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in pyrimidine-containing compound biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_510236.1

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The following sections contain reference sequences that belong to a specific genome build. Explain