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odr-7 Nuclear hormone receptor family member odr-7 [ Caenorhabditis elegans ]

Gene ID: 181403, updated on 23-Jan-2025

Summary

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Official Symbol
odr-7
Official Full Name
Nuclear hormone receptor family member odr-7
Primary source
WormBase:WBGene00003854
Locus tag
CELE_T18D3.2
See related
AllianceGenome:WB:WBGene00003854
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in negative adaptation of signaling pathway; positive chemotaxis; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in AWAL and AWAR. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See odr-7 in Genome Data Viewer
Location:
chromosome: X
Exon count:
6
Sequence:
Chromosome: X; NC_003284.9 (12458979..12461657, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene WD repeat-containing protein 89 Neighboring gene tRNA-Ala Neighboring gene ncRNA Neighboring gene Secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The C. elegans gene odr-7 encodes an olfactory-specific member of the nuclear receptor superfamily. Sengupta P, et al. Cell, 1994 Dec 16. PMID 8001144
  2. Evolution remodels olfactory and mating-receptive behaviors in the transition from female to hermaphrodite reproduction. Ebert MS, et al. Curr Biol, 2024 Mar 11. PMID 38340714
  3. Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey. Hsueh YP, et al. Elife, 2017 Jan 18. PMID 28098555, Free PMC Article
  4. Nematode genome sequence dramatically extends the nuclear receptor superfamily. Enmark E, et al. Trends Pharmacol Sci, 2000 Mar. PMID 10689360
  5. oxi-1 is required for chemotaxis to odorants sensed by AWA but not AWC neurons. Rana M, et al. MicroPubl Biol, 2024. PMID 39228993, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in negative adaptation of signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive chemotaxis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nuclear hormone receptor family member odr-7
NP_510089.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    12458979..12461657 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077688.4 → NP_510089.1  Nuclear hormone receptor family member odr-7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510089.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C3U4U8, C3U4U9, C3U4V2, P41933
    Conserved Domains (1) summary
    smart00399
    Location:330 → 403
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41933.1

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