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flp-7 TPMQRSSMVRF-amide 2 [ Caenorhabditis elegans ]

Gene ID: 180854, updated on 2-Nov-2024

Summary

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Official Symbol
flp-7
Official Full Name
TPMQRSSMVRF-amide 2
Primary source
WormBase:WBGene00001450
Locus tag
CELE_F49E10.3
See related
AllianceGenome:WB:WBGene00001450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables neuropeptide receptor binding activity. Involved in negative regulation of locomotion and neuropeptide signaling pathway. Located in extracellular space. Is expressed in nerve ring and neurons. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See flp-7 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (5885865..5886833)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mitochondria-eating protein C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Exploring the neurotransmitter labyrinth in nematodes. Brownlee DJ, et al. Trends Neurosci, 1999 Jan. PMID 10088995
  2. Head-tail-head neural wiring underlies gut fat storage in Caenorhabditis elegans temperature acclimation. Motomura H, et al. Proc Natl Acad Sci U S A, 2022 Aug 9. PMID 35914124, Free PMC Article
  3. Characterization of an RFamide-related peptide orphan GPCR in C. elegans. Mertens I, et al. Ann N Y Acad Sci, 2005 Apr. PMID 15891075
  4. Evolution and Comparative Physiology of Luqin-Type Neuropeptide Signaling. Yañez-Guerra LA, et al. Front Neurosci, 2020. PMID 32132900, Free PMC Article
  5. A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism. Palamiuc L, et al. Nat Commun, 2017 Jan 27. PMID 28128367, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables neuropeptide receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of locomotion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuropeptide signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in neuropeptide signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
TPMQRSSMVRF-amide 2
NP_508985.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    5885865..5886833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076584.6 → NP_508985.1  TPMQRSSMVRF-amide 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508985.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EEC2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EEC2.1

Gene LinkOut

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