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npr-16 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180643, updated on 2-Nov-2024

Summary

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Official Symbol
npr-16
Official Full Name
G-protein coupled receptors family 1 profile domain-containing protein
Primary source
WormBase:WBGene00006864
Locus tag
CELE_F56B6.5
See related
AllianceGenome:WB:WBGene00006864
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in anal depressor muscle; neurons; ventral nerve cord; and vm1. Orthologous to human SSTR3 (somatostatin receptor 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See npr-16 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (3522780..3531862)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene HMG box domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CC domain-containing protein Neighboring gene Glycogenin-1 Neighboring gene C2 domain-containing protein;RGS domain-containing protein;Regulator of G-protein signaling rgs-7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of regions of the Caenorhabditis elegans X chromosome containing vitellogenin genes. Heine U, et al. J Mol Biol, 1986 Apr 5. PMID 3735423
  2. Identification of novel target genes of CeTwist and CeE/DA. Wang P, et al. Dev Biol, 2006 May 15. PMID 16480708
  3. Cannabinoids activate the insulin pathway to modulate mobilization of cholesterol in C. elegans. Hernandez-Cravero B, et al. PLoS Genet, 2022 Nov. PMID 36346800, Free PMC Article
  4. Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Styer KL, et al. Science, 2008 Oct 17. PMID 18801967, Free PMC Article
  5. A gene expression fingerprint of C. elegans embryonic motor neurons. Fox RM, et al. BMC Genomics, 2005 Mar 21. PMID 15780142, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
G-protein coupled receptors family 1 profile domain-containing protein
NP_001041258.1
  • Confirmed by transcript evidence
NP_001041259.1
  • Confirmed by transcript evidence
NP_001355489.1
  • Confirmed by transcript evidence
NP_001355490.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    3522780..3531862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001368498.3 → NP_001355490.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3B1DQQ4
    Conserved Domains (1) summary
    cd00637
    Location:45 → 305
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

  2. NM_001368499.4 → NP_001355489.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3B1E8V2
    Conserved Domains (1) summary
    cd00637
    Location:45 → 305
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

  3. NM_001047793.6 → NP_001041258.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041258.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22995
    Conserved Domains (1) summary
    cd00637
    Location:35 → 295
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily

  4. NM_001047794.5 → NP_001041259.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041259.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2V4S5
    Conserved Domains (1) summary
    cd00637
    Location:35 → 295
    7tm_classA_rhodopsin-like; rhodopsin receptor-like class A family of the seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein
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