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rsef-1 Ras and EF-hand domain-containing protein homolog [ Caenorhabditis elegans ]

Gene ID: 180593, updated on 4-Jan-2025

Summary

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Official Symbol
rsef-1
Official Full Name
Ras and EF-hand domain-containing protein homolog
Primary source
WormBase:WBGene00016344
Locus tag
CELE_C33D12.6
See related
AllianceGenome:WB:WBGene00016344
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in perinuclear region of cytoplasm. Is expressed in g1; spermathecal-uterine junction; and uterus. Orthologous to several human genes including RASEF (RAS and EF-hand domain containing). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See rsef-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
13
Sequence:
Chromosome: X; NC_003284.9 (3055156..3059399, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Potassium channel domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Homeobox protein ceh-30

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatial and molecular cues for cell outgrowth during C. elegans uterine development. Ghosh S, et al. Dev Biol, 2014 Dec 1. PMID 25281934
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ras and EF-hand domain-containing protein homolog
NP_001359915.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    3055156..3059399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373254.3 → NP_001359915.1  Ras and EF-hand domain-containing protein homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q21466, Q22906, Q22908
    UniProtKB/TrEMBL
    I7FXE3
    Conserved Domains (3) summary
    cd00154
    Location:440 → 600
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
    COG1196
    Location:155 → 362
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam13499
    Location:3 → 63
    EF-hand_7; EF-hand domain pair
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22908.3

Gene LinkOut

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