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ccd-5 C2 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180558, updated on 2-Nov-2024

Summary

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Official Symbol
ccd-5
Official Full Name
C2 domain-containing protein
Primary source
WormBase:WBGene00018719
Locus tag
CELE_F52H2.7
See related
AllianceGenome:WB:WBGene00018719
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity and calcium-dependent phospholipid binding activity. Predicted to be involved in several processes, including intracellular protein transmembrane transport; positive regulation of protein targeting to membrane; and positive regulation of transport. Predicted to be active in plasma membrane. Orthologous to human C2CD5 (C2 calcium dependent domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ccd-5 in Genome Data Viewer
Location:
chromosome: X
Exon count:
16
Sequence:
Chromosome: X; NC_003284.9 (2566543..2572653, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Diminuto-like protein;FAD-binding PCMH-type domain-containing protein Neighboring gene Leucine-rich single-pass membrane protein 1 Neighboring gene JmjC domain-containing protein Neighboring gene ncRNA Neighboring gene SET domain-containing protein Neighboring gene Transthyretin-like family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans. Feresten AH, et al. Genetics, 2022 Apr 4. PMID 35143653, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans.
    Title: ccd-5, a novel cdk-5 binding partner, regulates pioneer axon guidance in the ventral nerve cord of Caenorhabditis elegans.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium-dependent phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in intracellular protein transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of D-glucose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of vesicle fusion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
C2 domain-containing protein
NP_001360059.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    2566543..2572653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373248.4 → NP_001360059.1  C2 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17398
    Conserved Domains (1) summary
    cd08688
    Location:14 → 127
    C2_KIAA0528-like; C2 domain found in the Human KIAA0528 cDNA clone
Nucleotide Protein
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