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abhd-3.2 AB hydrolase-1 domain-containing protein;Protein abhd-3.2 [ Caenorhabditis elegans ]

Gene ID: 180450, updated on 4-Jan-2025

Summary

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Official Symbol
abhd-3.2
Official Full Name
AB hydrolase-1 domain-containing protein;Protein abhd-3.2
Primary source
WormBase:WBGene00016644
Locus tag
CELE_C44C1.5
See related
AllianceGenome:WB:WBGene00016644
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable acetylesterase activity and monoacylglycerol lipase activity. Predicted to be involved in medium-chain fatty acid biosynthetic process and medium-chain fatty acid catabolic process. Orthologous to human ABHD1 (abhydrolase domain containing 1) and ABHD3 (abhydrolase domain containing 3, phospholipase). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See abhd-3.2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (975525..978008, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Neuropeptide-Like Protein Neighboring gene Vacuolar protein sorting-associated protein 45 Neighboring gene ncRNA Neighboring gene G protein-coupled receptor Neighboring gene Diacylglycerol kinase Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Starvation-induced changes in somatic insulin/IGF-1R signaling drive metabolic programming across generations. Vogt MC, et al. Sci Adv, 2023 Apr 7. PMID 37027477, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables acetylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carboxylic ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables monoacylglycerol lipase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in medium-chain fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in medium-chain fatty acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
AB hydrolase-1 domain-containing protein;Protein abhd-3.2
NP_001024458.1
  • Confirmed by transcript evidence
NP_001024459.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    975525..978008 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029287.7 → NP_001024458.1  Protein abhd-3.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024458.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18610
    Conserved Domains (2) summary
    pfam00561
    Location:108 → 351
    Abhydrolase_1; alpha/beta hydrolase fold
    cl21494
    Location:56 → 366
    Abhydrolase; alpha/beta hydrolases

  2. NM_001029288.5 → NP_001024459.1  AB hydrolase-1 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024459.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G8JY22
    Conserved Domains (1) summary
    cl21494
    Location:56 → 249
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18610.1

Gene LinkOut

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