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ndua-1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [ Caenorhabditis elegans ]

Gene ID: 180372, updated on 9-Dec-2024

Summary

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Official Symbol
ndua-1
Official Full Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Primary source
WormBase:WBGene00009294
Locus tag
CELE_F31D4.9
See related
AllianceGenome:WB:WBGene00009294
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in membrane. Predicted to be part of respiratory chain complex I. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ndua-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (20850877..20851897, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ribosomal RNA-processing protein 42 Neighboring gene Sugar phosphate phosphatase Neighboring gene peptidylprolyl isomerase Neighboring gene C-type lectin domain-containing protein Neighboring gene Pleckstrin homology domain-containing family D member 1 Neighboring gene Peptidase S1 domain-containing protein Neighboring gene Potassium channel domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C. elegans as a model organism for human mitochondrial associated disorders. Maglioni S, et al. Mitochondrion, 2016 Sep. PMID 26906059
  2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
NP_508028.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20850877..20851897 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_075627.7 → NP_508028.2  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508028.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U3H4
    Conserved Domains (1) summary
    pfam15879
    Location:4 → 55
    MWFE; NADH-ubiquinone oxidoreductase MWFE subunit
Nucleotide Protein
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