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syp-1 Uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 180102, updated on 9-Dec-2024

Summary

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Official Symbol
syp-1
Official Full Name
Uncharacterized protein
Primary source
WormBase:WBGene00006375
Locus tag
CELE_F26D2.2
See related
AllianceGenome:WB:WBGene00006375
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables protein homodimerization activity. Involved in positive regulation of reciprocal meiotic recombination; regulation of chromosome segregation; and synaptonemal complex assembly. Located in central element. Is expressed in germ line and gonad. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See syp-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (16404274..16407701)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Methyltransferase FkbM domain-containing protein Neighboring gene Serpentine Receptor, class E (Epsilon) Neighboring gene BZIP domain-containing protein Neighboring gene ncRNA Neighboring gene Core-2/I-Branching enzyme Neighboring gene Serpentine Receptor, class H

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Chromosome-wide regulation of meiotic crossover formation in Caenorhabditis elegans requires properly assembled chromosome axes. Nabeshima K, et al. Genetics, 2004 Nov. PMID 15579685, Free PMC Article
  2. The synaptonemal complex shapes the crossover landscape through cooperative assembly, crossover promotion and crossover inhibition during Caenorhabditis elegans meiosis. Hayashi M, et al. Genetics, 2010 Sep. PMID 20592266, Free PMC Article
  3. Assembly of the Synaptonemal Complex Is a Highly Temperature-Sensitive Process That Is Supported by PGL-1 During Caenorhabditis elegans Meiosis. Bilgir C, et al. G3 (Bethesda), 2013 Apr 9. PMID 23550120, Free PMC Article
  4. A suppressor screen in C. elegans identifies a multiprotein interaction that stabilizes the synaptonemal complex. Kursel LE, et al. Proc Natl Acad Sci U S A, 2023 Dec 12. PMID 38055743, Free PMC Article
  5. Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans. MacQueen AJ, et al. Genes Dev, 2002 Sep 15. PMID 12231631, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synaptonemal complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in central element IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synaptonemal complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Uncharacterized protein
NP_507145.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    16404274..16407701
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074744.7 → NP_507145.2  Uncharacterized protein CELE_F26D2.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_507145.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EGS8
    Conserved Domains (1) summary
    TIGR04527
    Location:316 → 417
    mycoplas_twoTM; two transmembrane protein
Nucleotide Protein
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