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hil-1 Histone H1.X [ Caenorhabditis elegans ]

Gene ID: 179993, updated on 4-Jan-2025

Summary

Official Symbol
hil-1
Official Full Name
Histone H1.X
Primary source
WormBase:WBGene00001852
Locus tag
CELE_C30G7.1
See related
AllianceGenome:WB:WBGene00001852
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Involved in several processes, including body morphogenesis; egg-laying behavior; and pharynx development. Located in intermediate filament cytoskeleton and nucleolus. Is expressed in several structures, including body wall musculature; excretory system; head neurons; marginal cell; and vulval muscle. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See hil-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (14949777..14952799)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Matrix-remodeling-associated protein 7 Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ADP-ribosylation factor-like protein 6-interacting protein 4

General gene information

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleosomal DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in body morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in chromosome condensation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in egg-laying behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of DNA recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nucleosome assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in pharynx development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in intermediate filament cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Histone H1.X
NP_506680.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14949777..14952799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074279.7NP_506680.1  Histone H1.X [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506680.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O02556, Q18336
    Conserved Domains (2) summary
    pfam00538
    Location:37111
    Linker_histone; linker histone H1 and H5 family
    cl21453
    Location:96140
    PKc_like; Protein Kinases, catalytic domain