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ric-7 CRAL-TRIO domain-containing protein;DUF1336 domain-containing protein;Uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 179894, updated on 9-Dec-2024

Summary

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Official Symbol
ric-7
Official Full Name
CRAL-TRIO domain-containing protein;DUF1336 domain-containing protein;Uncharacterized protein
Primary source
WormBase:WBGene00010259
Locus tag
CELE_F58E10.1
See related
AllianceGenome:WB:WBGene00010259
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in several processes, including positive regulation of protein localization to presynapse; positive regulation of synapse pruning; and secretion by cell. Located in mitochondrion and synapse. Is expressed in head muscle and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ric-7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
14
Sequence:
Chromosome: V; NC_003283.11 (13987164..14005912, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene GATA-type domain-containing protein Neighboring gene dietary restriction over expressed Neighboring gene RNA helicase Neighboring gene AN1-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport. Wu Y, et al. J Cell Biol, 2024 May 6. PMID 38470363, Free PMC Article
  2. nu444 is a novel allele of pkc-1 in C. elegans. Wang H, et al. MicroPubl Biol, 2017 May 18. PMID 32550344, Free PMC Article
  3. RIC-7 promotes neuropeptide secretion. Hao Y, et al. PLoS Genet, 2012 Jan. PMID 22275875, Free PMC Article
  4. Axons degenerate in the absence of mitochondria in C. elegans. Rawson RL, et al. Curr Biol, 2014 Mar 31. PMID 24631238, Free PMC Article
  5. The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons. Meng L, et al. Cell Rep, 2015 Jun 23. PMID 26074078, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport.
    Title: Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in actin filament depolymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in dense core granule exocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitochondrion localization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in peptide secretion, neurotransmission IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of defecation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of defecation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of locomotion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of protein localization to presynapse IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of synapse pruning IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of muscle contraction IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of synapse organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
  
located_in synapse IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
CRAL-TRIO domain-containing protein;DUF1336 domain-containing protein;Uncharacterized protein
NP_001041132.1
  • Confirmed by transcript evidence
NP_001041133.1
  • Confirmed by transcript evidence
NP_001294709.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    13987164..14005912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047667.5 → NP_001041132.1  DUF1336 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041132.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XUW6

  2. NM_001047668.6 → NP_001041133.1  CRAL-TRIO domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041133.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q1ZXS6

  3. NM_001307780.3 → NP_001294709.1  Uncharacterized protein CELE_F58E10.1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294709.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    N1NSI8
Nucleotide Protein
Heading Accession and Version

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