syx-5 Putative syntaxin-5 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: syx-5
Official Full Name: Putative syntaxin-5
Primary source: WormBase:WBGene00006373
Locus tag: CELE_F55A11.2
See related: AllianceGenome:WB:WBGene00006373
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable SNAP receptor activity and SNARE binding activity. Predicted to be involved in several processes, including endoplasmic reticulum to Golgi vesicle-mediated transport; synaptic vesicle docking; and vesicle fusion. Predicted to be located in membrane and presynapse. Predicted to be part of SNARE complex. Predicted to be active in Golgi membrane. Is expressed in several structures, including anal depressor muscle; excretory gland cell; nervous system; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human STX5 (syntaxin 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See syx-5 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 5

Sequence:: Chromosome: V; NC_003283.11 (11764904..11767222)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F55A11.1 (e-PCR)
- UniSTS:315927

F55A11.2 (e-PCR)
- UniSTS:311805

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables SNAP receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables SNARE binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in neurotransmitter transport	IEA Inferred from Electronic Annotation more info
involved_in synaptic vesicle docking	ISS Inferred from Sequence or Structural Similarity more info
involved_in vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in presynapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Putative syntaxin-5

NP_505968.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

11764904..11767222

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_073567.9 → NP_505968.1 Putative syntaxin-5 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_505968.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q20797

Conserved Domains (2) summary

COG5325
Location:123 → 382

COG5325; t-SNARE complex subunit, syntaxin [Intracellular trafficking and secretion]

cd15844
Location:324 → 396

SNARE_syntaxin5; SNARE motif of syntaxin 5