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D1054.3 SGS domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179494, updated on 9-Dec-2024

Summary

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Official Symbol
D1054.3
Official Full Name
SGS domain-containing protein
Primary source
WormBase:WBGene00008371
Locus tag
CELE_D1054.3
See related
AllianceGenome:WB:WBGene00008371
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein-folding chaperone binding activity. Orthologous to human SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See D1054.3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (10771451..10772832)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ANK_REP_REGION domain-containing protein;Ion transport domain-containing protein Neighboring gene PNPLA domain-containing protein Neighboring gene Proteasome subunit alpha type-2 Neighboring gene ncRNA Neighboring gene CBS domain-containing protein Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nematode Sgt1-homologue D1054.3 binds open and closed conformations of Hsp90 via distinct binding sites. Eckl JM, et al. Biochemistry, 2014 Apr 22. PMID 24660900
  2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SGS domain-containing protein
NP_001263858.1
  • Confirmed by transcript evidence
NP_505751.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10771451..10772832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073350.6 → NP_505751.1  SGS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505751.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18949
    Conserved Domains (1) summary
    PLN03088
    Location:3 → 197
    PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

  2. NM_001276929.3 → NP_001263858.1  SGS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263858.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    J7RNI7
    Conserved Domains (1) summary
    pfam05002
    Location:1 → 54
    SGS; SGS domain
Nucleotide Protein
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