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yif-1 Protein YIF1 [ Caenorhabditis elegans ]

Gene ID: 179400, updated on 2-Nov-2024

Summary

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Official Symbol
yif-1
Official Full Name
Protein YIF1
Primary source
WormBase:WBGene00010178
Locus tag
CELE_F57A8.2
See related
AllianceGenome:WB:WBGene00010178
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in linker cell. Used to study Parkinson's disease. Orthologous to several human genes including YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See yif-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
8
Sequence:
Chromosome: V; NC_003283.11 (10050047..10054913, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein TSSC4 Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Seven TM Receptor Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Nuclear receptor domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum-Golgi intermediate compartment IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein YIF1
NP_001041126.1
  • Confirmed by transcript evidence
NP_001041127.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    10050047..10054913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047662.4 → NP_001041127.1  Protein YIF1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041127.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PJ77
    Conserved Domains (1) summary
    pfam03878
    Location:103 → 323
    YIF1; YIF1

  2. NM_001047661.5 → NP_001041126.1  Protein YIF1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041126.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20913
    Conserved Domains (1) summary
    pfam03878
    Location:103 → 323
    YIF1; YIF1
Nucleotide Protein
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