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her-1 Protein her-1 [ Caenorhabditis elegans ]

Gene ID: 179360, updated on 4-Jan-2025

Summary

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Official Symbol
her-1
Official Full Name
Protein her-1
Primary source
WormBase:WBGene00001842
Locus tag
CELE_ZK287.8
See related
AllianceGenome:WB:WBGene00001842
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables signaling receptor binding activity. Involved in male sex determination. Located in extracellular region. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See her-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (9697015..9702035)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RNA_ligase domain-containing protein Neighboring gene Protein lifeguard 1-like Neighboring gene Transmembrane BAX inhibitor motif-containing protein 4 Neighboring gene tRNA wybutosine-synthesizing protein 2 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequenced alleles of the Caenorhabditis elegans sex-determining gene her-1 include a novel class of conditional promoter mutations. Perry MD, et al. Genetics, 1994 Oct. PMID 7828816, Free PMC Article
  2. A Simple Method for Visualization of Locus-Specific H4K20me1 Modifications in Living Caenorhabditis elegans Single Cells. Shinkai Y, et al. G3 (Bethesda), 2018 Jul 2. PMID 29724885, Free PMC Article
  3. A novel dominant transformer allele of the sex-determining gene her-1 of Caenorhabditis elegans. Trent C, et al. Genetics, 1988 Sep. PMID 3220248, Free PMC Article
  4. Structure of the RECK CC domain, an evolutionary anomaly. Chang TH, et al. Proc Natl Acad Sci U S A, 2020 Jun 30. PMID 32541044, Free PMC Article
  5. Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A. Hamaoka BY, et al. Proc Natl Acad Sci U S A, 2004 Aug 10. PMID 15289613, Free PMC Article

See all (130) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in male sex determination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in male sex determination IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in male sex determination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein her-1
NP_001024310.1
  • Confirmed by transcript evidence
NP_001024311.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9697015..9702035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029139.3 → NP_001024310.1  Protein her-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024310.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34704
    Conserved Domains (1) summary
    pfam09232
    Location:32 → 162
    Caenor_Her-1; Caenorhabditis elegans Her-1

  2. NM_001029140.5 → NP_001024311.2  Protein her-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024311.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q65ZB2
    Conserved Domains (1) summary
    pfam09232
    Location:1 → 51
    Caenor_Her-1; Caenorhabditis elegans Her-1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34704.1

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