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tag-153 NOT2/NOT3/NOT5 C-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179312, updated on 9-Dec-2024

Summary

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Official Symbol
tag-153
Official Full Name
NOT2/NOT3/NOT5 C-terminal domain-containing protein
Primary source
WormBase:WBGene00006499
Locus tag
CELE_F44A2.1
See related
AllianceGenome:WB:WBGene00006499
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening and regulation of stem cell population maintenance. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See tag-153 in Genome Data Viewer
Location:
chromosome: V
Exon count:
14
Sequence:
Chromosome: V; NC_003283.11 (9323085..9327213)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene BTB domain-containing protein Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene Phospholipid/glycerol acyltransferase domain-containing protein Neighboring gene Acyltransferase Neighboring gene UnCoupling Protein (mitochondrial substrate carrier)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2. Lo TW, et al. Genetics, 2010 Jun. PMID 20308281, Free PMC Article
  2. COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in Caenorhabditis elegans germline stem and progenitor cells. Osterli E, et al. Genetics, 2024 May 7. PMID 38427913,
  3. LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans. Tsukamoto T, et al. Genetics, 2017 Aug. PMID 28576864, Free PMC Article
  4. ITSN-1 controls vesicle recycling at the neuromuscular junction and functions in parallel with DAB-1. Wang W, et al. Traffic, 2008 May. PMID 18298590, Free PMC Article
  5. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of stem cell population maintenance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of stem cell population maintenance IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of CCR4-NOT core complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of CCR4-NOT core complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NOT2/NOT3/NOT5 C-terminal domain-containing protein
NP_505409.1
  • Confirmed by transcript evidence
NP_505410.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9323085..9327213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073008.7 → NP_505409.1  NOT2/NOT3/NOT5 C-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505409.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L031
    Conserved Domains (1) summary
    cl02384
    Location:439 → 532
    NOT2_3_5; NOT2 / NOT3 / NOT5 family

  2. NM_073009.6 → NP_505410.1  NOT2/NOT3/NOT5 C-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505410.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q27420
    Conserved Domains (1) summary
    cl02384
    Location:203 → 291
    NOT2_3_5; NOT2 / NOT3 / NOT5 family
Nucleotide Protein
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