sel-9 Suppressor/enhancer of lin-12 protein 9 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: sel-9
Official Full Name: Suppressor/enhancer of lin-12 protein 9
Primary source: WormBase:WBGene00004766
Locus tag: CELE_W02D7.7
See related: AllianceGenome:WB:WBGene00004766
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of Notch signaling pathway; and regulation of transport. Predicted to be located in COPI-coated vesicle membrane and Golgi membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including excretory system; hermaphrodite gonad; hypodermis; nervous system; and pharynx. Orthologous to human TMED2 (transmembrane p24 trafficking protein 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See sel-9 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 4

Sequence:: Chromosome: V; NC_003283.11 (8301490..8302580, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W02D7.7 (e-PCR)
- UniSTS:317228

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in Golgi organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of Notch signaling pathway	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in COPI-coated vesicle membrane	IEA Inferred from Electronic Annotation more info
is_active_in COPII-coated ER to Golgi transport vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in ER to Golgi transport vesicle membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum-Golgi intermediate compartment	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Suppressor/enhancer of lin-12 protein 9

NP_001370673.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

8301490..8302580 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001383355.2 → NP_001370673.1 Suppressor/enhancer of lin-12 protein 9 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

O17528

Conserved Domains (1) summary

pfam01105
Location:21 → 198

EMP24_GP25L; emp24/gp25L/p24 family/GOLD