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pmp-5 ABC transmembrane type-1 domain-containing protein;ABC transporter domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179056, updated on 4-Jan-2025

Summary

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Official Symbol
pmp-5
Official Full Name
ABC transmembrane type-1 domain-containing protein;ABC transporter domain-containing protein
Primary source
WormBase:WBGene00004062
Locus tag
CELE_T10H9.5
See related
AllianceGenome:WB:WBGene00004062
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transmembrane transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in membrane. Predicted to be active in peroxisomal membrane. Is expressed in hypodermis and intestine. Orthologous to human ABCD4 (ATP binding cassette subfamily D member 4). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See pmp-5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
13
Sequence:
Chromosome: V; NC_003283.11 (6662191..6665813, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Seven TM Receptor Neighboring gene Carboxylic ester hydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The effects of nested miRNAs and their host genes on immune defense against Bacillus thuringiensis infection in Caenorhabditis elegans. Zárate-Potes A, et al. Dev Comp Immunol, 2021 Oct. PMID 34051205
  2. Role of NH2-terminal hydrophobic motif in the subcellular localization of ATP-binding cassette protein subfamily D: common features in eukaryotic organisms. Lee A, et al. Biochem Biophys Res Commun, 2014 Oct 24. PMID 25301552
  3. Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor. Giese GE, et al. Elife, 2020 Oct 5. PMID 33016879, Free PMC Article
  4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables long-chain fatty acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty acid import into peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peroxisome organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in very long-chain fatty acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ABC transmembrane type-1 domain-containing protein;ABC transporter domain-containing protein
NP_001024131.1
  • Confirmed by transcript evidence
NP_504689.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6662191..6665813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072288.7 → NP_504689.1  ABC transporter domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504689.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L034
    Conserved Domains (1) summary
    COG4178
    Location:33 → 582
    YddA; ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]

  2. NM_001028960.6 → NP_001024131.1  ABC transmembrane type-1 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024131.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L035
    Conserved Domains (1) summary
    COG4178
    Location:33 → 561
    YddA; ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]
Nucleotide Protein
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