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syx-18 t-SNARE coiled-coil homology domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179055, updated on 4-Jan-2025

Summary

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Official Symbol
syx-18
Official Full Name
t-SNARE coiled-coil homology domain-containing protein
Primary source
WormBase:WBGene00020425
Locus tag
CELE_T10H9.3
See related
AllianceGenome:WB:WBGene00020425
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in endoplasmic reticulum. Orthologous to human STX18 (syntaxin 18). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See syx-18 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (6653613..6655449, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ALK tyrosine kinase receptor homolog scd-2 Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene EF-hand domain-containing protein Neighboring gene Synaptobrevin-1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The SM protein VPS-45 is required for RAB-5-dependent endocytic transport in Caenorhabditis elegans. Gengyo-Ando K, et al. EMBO Rep, 2007 Feb. PMID 17235359, Free PMC Article
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
t-SNARE coiled-coil homology domain-containing protein
NP_504687.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6653613..6655449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072286.6 → NP_504687.1  t-SNARE coiled-coil homology domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504687.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76413
    Conserved Domains (1) summary
    cl22856
    Location:326 → 384
    SNARE; SNARE motif
Nucleotide Protein
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