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ceh-49 One cut domain family member [ Caenorhabditis elegans ]

Gene ID: 179001, updated on 4-Jan-2025

Summary

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Official Symbol
ceh-49
Official Full Name
One cut domain family member
Primary source
WormBase:WBGene00017538
Locus tag
CELE_F17A9.6
See related
AllianceGenome:WB:WBGene00017538
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in coelomocyte; head muscle; head neurons; intestine; and somatic nervous system. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ceh-49 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (6118333..6120206, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CWF19-like protein 1 homolog Neighboring gene NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein Neighboring gene pseudo Neighboring gene Ig-like domain-containing protein;Titin;Titin homolog Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss and gain of domains during evolution of cut superclass homeobox genes. Bürglin TR, et al. Int J Dev Biol, 2002 Jan. PMID 11902672
  2. Robust regulatory architecture of pan-neuronal gene expression. Leyva-Díaz E, et al. Curr Biol, 2022 Apr 25. PMID 35259341, Free PMC Article
  3. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article
  4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  5. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
One cut domain family member
NP_504581.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6118333..6120206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072180.5 → NP_504581.1  One cut domain family member [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504581.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16218
    Conserved Domains (2) summary
    smart00389
    Location:248 → 302
    HOX; Homeodomain
    pfam02376
    Location:149 → 232
    CUT; CUT domain
Nucleotide Protein
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