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nhr-115 NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-115 [ Caenorhabditis elegans ]

Gene ID: 178708, updated on 9-Dec-2024

Summary

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Official Symbol
nhr-115
Official Full Name
NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-115
Primary source
WormBase:WBGene00003705
Locus tag
CELE_T27B7.4
See related
AllianceGenome:WB:WBGene00003705
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in innate immune response. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See nhr-115 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (2292540..2294800)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene NR LBD domain-containing protein Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  3. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in innate immune response HEP PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NR LBD domain-containing protein;Nuclear hormone receptor family member nhr-115
NP_001256014.1
  • Confirmed by transcript evidence
NP_001370855.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2292540..2294800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269085.2 → NP_001256014.1  Nuclear hormone receptor family member nhr-115 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256014.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O16662, Q86PI5
    Conserved Domains (2) summary
    smart00399
    Location:7 → 73
    ZnF_C4; c4 zinc finger in nuclear hormone receptors
    pfam00104
    Location:160 → 365
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor

  2. NM_001383285.2 → NP_001370855.1  NR LBD domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7E2K2
    Conserved Domains (1) summary
    pfam00104
    Location:91 → 302
    Hormone_recep; Ligand-binding domain of nuclear hormone receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O16662.3

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