T10B5.3 Small-subunit processome Utp12 domain-containing protein;Utp12 domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T10B5.3
Official Full Name: Small-subunit processome Utp12 domain-containing protein;Utp12 domain-containing protein
Primary source: WormBase:WBGene00020389
Locus tag: CELE_T10B5.3
See related: AllianceGenome:WB:WBGene00020389
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in membrane and nucleus. Predicted to be active in nucleolus. Orthologous to human WDR43 (WD repeat domain 43). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See T10B5.3 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 5

Sequence:: Chromosome: V; NC_003283.11 (1864178..1868571, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T10B5.3 (e-PCR)
- UniSTS:310774

T10B5.6 (e-PCR)
- UniSTS:310775

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Small-subunit processome Utp12 domain-containing protein;Utp12 domain-containing protein

NP_001300191.1

Confirmed by transcript evidence

NP_503519.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

1864178..1868571 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_071118.5 → NP_503519.2 Small-subunit processome Utp12 domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_503519.2

Status: REVIEWED

UniProtKB/TrEMBL

O76407

Conserved Domains (1) summary

pfam04003
Location:94 → 191

Utp12; Dip2/Utp12 Family
NM_001313262.3 → NP_001300191.1 Utp12 domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3AV49