U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gid-8 CTLH domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178639, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
gid-8
Official Full Name
CTLH domain-containing protein
Primary source
WormBase:WBGene00018757
Locus tag
CELE_F53E2.1
See related
AllianceGenome:WB:WBGene00018757
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Located in nucleus. Is expressed in body wall musculature; nervous system; pharynx; reproductive system; and seam cell. Orthologous to human GID8 (GID complex subunit 8 homolog). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gid-8 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (1467744..1471105)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Solute carrier family 40 member Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Actin-depolymerizing factor 1 Neighboring gene Actin-depolymerizing factor 2 Neighboring gene non-specific serine/threonine protein kinase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
CTLH domain-containing protein
NP_001300116.1
  • Confirmed by transcript evidence
NP_503424.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    1467744..1471105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071023.6 → NP_503424.2  CTLH domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503424.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9UAU3
    Conserved Domains (4) summary
    smart00667
    Location:168 → 201
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:212 → 264
    CTLH; C-terminal to LisH motif
    smart00757
    Location:260 → 340
    CRA; CT11-RanBPM
    pfam10607
    Location:209 → 342
    CLTH; CTLH/CRA C-terminal to LisH motif domain

  2. NM_001313187.3 → NP_001300116.1  CTLH domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0K3AUY3
    Conserved Domains (4) summary
    smart00667
    Location:5 → 38
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:49 → 101
    CTLH; C-terminal to LisH motif
    smart00757
    Location:97 → 177
    CRA; CT11-RanBPM
    pfam10607
    Location:46 → 179
    CLTH; CTLH/CRA C-terminal to LisH motif domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools