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Y41E3.8 Glycine Rich Secreted Protein [ Caenorhabditis elegans ]

Gene ID: 178417, updated on 4-Jan-2025

Summary

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Official Symbol
Y41E3.8
Official Full Name
Glycine Rich Secreted Protein
Primary source
WormBase:WBGene00012766
Locus tag
CELE_Y41E3.8
See related
AllianceGenome:WB:WBGene00012766
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Orthologous to human SELENOK (selenoprotein K). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Y41E3.8 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (15028358..15028978, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Glutaminyl-tRNA synthetase;Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding domain-containing protein;glutamine--tRNA ligase;putative glutamine--tRNA ligase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ACB domain-containing protein;GOLD domain-containing protein;Golgi resident protein GCP60 Neighboring gene FANCD2 Neighboring gene ncRNA Neighboring gene putative elongation factor 1-beta/1-delta 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
acts_upstream_of_or_within IRE1-mediated unfolded protein response HEP PubMed 
involved_in calcium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Glycine Rich Secreted Protein
NP_001294102.1
  • Confirmed by transcript evidence
NP_502815.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    15028358..15028978 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070414.7 → NP_502815.1  Glycine Rich Secreted Protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502815.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62437
    Conserved Domains (1) summary
    pfam10961
    Location:2 → 54
    DUF2763; Protein of unknown function (DUF2763)

  2. NM_001307173.3 → NP_001294102.1  Glycine Rich Secreted Protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294102.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A078BTL4
    Conserved Domains (1) summary
    pfam10961
    Location:1 → 34
    DUF2763; Protein of unknown function (DUF2763)
Nucleotide Protein
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