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gly-10 Putative polypeptide N-acetylgalactosaminyltransferase 10;Ricin B lectin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178343, updated on 2-Nov-2024

Summary

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Official Symbol
gly-10
Official Full Name
Putative polypeptide N-acetylgalactosaminyltransferase 10;Ricin B lectin domain-containing protein
Primary source
WormBase:WBGene00001635
Locus tag
CELE_Y45F10D.3
See related
AllianceGenome:WB:WBGene00001635
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to several human genes including GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gly-10 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (13779096..13782396)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Large ribosomal subunit protein eL18 Neighboring gene Beta-lactamase-related domain-containing protein Neighboring gene NIF system FeS cluster assembly NifU N-terminal domain-containing protein Neighboring gene Integrin Cytoplasmic domain-Associated Protein homolog Neighboring gene Spindle assembly abnormal protein 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The terminal phase of cytokinesis in the Caenorhabditis elegans early embryo requires protein glycosylation. Wang H, et al. Mol Biol Cell, 2005 Sep. PMID 15987734, Free PMC Article
  2. Evolutionary conservation of putative suicidality-related risk genes that produce diminished motivation corrected by clozapine, lithium and antidepressants. Ajayi T, et al. Front Psychiatry, 2024. PMID 38362034, Free PMC Article
  3. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
  4. Increasing Complexity of the N-Glycome During Caenorhabditis Development. Wilson IBH, et al. Mol Cell Proteomics, 2023 Mar. PMID 36717059, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables polypeptide N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables polypeptide N-acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative polypeptide N-acetylgalactosaminyltransferase 10;Ricin B lectin domain-containing protein
NP_001041036.2
  • Partially confirmed by transcript evidence
NP_001041037.1
  • Confirmed by transcript evidence
NP_001293853.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13779096..13782396
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047571.4 → NP_001041036.2  Putative polypeptide N-acetylgalactosaminyltransferase 10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041036.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O45947, Q2HQM0
    Conserved Domains (3) summary
    cd02510
    Location:241 → 539
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:557 → 681
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:555 → 681
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

  2. NM_001047572.4 → NP_001041037.1  Putative polypeptide N-acetylgalactosaminyltransferase 10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041037.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O45947, Q2HQM0
    Conserved Domains (3) summary
    cd02510
    Location:160 → 458
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:476 → 600
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:474 → 600
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain

  3. NM_001306924.3 → NP_001293853.1  Ricin B lectin domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293853.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    S6FN25
    Conserved Domains (2) summary
    pfam00652
    Location:145 → 271
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    cl11394
    Location:1 → 129
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
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