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scl-2 SCP domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178251, updated on 9-Dec-2024

Summary

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Official Symbol
scl-2
Official Full Name
SCP domain-containing protein
Primary source
WormBase:WBGene00009895
Locus tag
CELE_F49E11.10
See related
AllianceGenome:WB:WBGene00009895
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in extracellular space. Is expressed in intestinal cell. Orthologous to several human genes including PI15 (peptidase inhibitor 15). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See scl-2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (13057710..13059062)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene SCP domain-containing protein Neighboring gene SCP domain-containing protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake. Laing ST, et al. PLoS One, 2012. PMID 22348077, Free PMC Article
  2. Physiological and Immunological Regulations in Caenorhabditis elegans Infected with Salmonella enterica serovar Typhi. Sivamaruthi BS, et al. Indian J Microbiol, 2014 Mar. PMID 24426167, Free PMC Article
  3. Alterations in Caenorhabditis elegans and Cronobacter sakazakii lipopolysaccharide during interaction. Sivamaruthi BS, et al. Arch Microbiol, 2015 Mar. PMID 25416126
  4. Proton Microbeam Targeted Irradiation of the Gonad Primordium Region Induces Developmental Alterations Associated with Heat Shock Responses and Cuticle Defense in Caenorhabditis elegans. Beaudier P, et al. Biology (Basel), 2023 Oct 27. PMID 37997971, Free PMC Article
  5. Identification and characterization of differentially expressed genes in Caenorhabditis elegans in response to pathogenic and nonpathogenic Stenotrophomonas maltophilia. Radeke LJ, et al. BMC Microbiol, 2020 Jun 19. PMID 32560629, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SCP domain-containing protein
NP_001263803.1
  • Partially confirmed by transcript evidence
NP_502503.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13057710..13059062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_070102.7 → NP_502503.1  SCP domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502503.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20603
    Conserved Domains (1) summary
    smart00198
    Location:21 → 174
    SCP; SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains

  2. NM_001276874.3 → NP_001263803.1  SCP domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263803.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    J7RNK2
    Conserved Domains (1) summary
    cl00133
    Location:7 → 49
    CAP; CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family
Nucleotide Protein
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