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F07C6.4 Cytohesin Ubiquitin Protein Inducing domain-containing protein;FERM domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178235, updated on 2-Nov-2024

Summary

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Official Symbol
F07C6.4
Official Full Name
Cytohesin Ubiquitin Protein Inducing domain-containing protein;FERM domain-containing protein
Primary source
WormBase:WBGene00008555
Locus tag
CELE_F07C6.4
See related
AllianceGenome:WB:WBGene00008555
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in establishment of epithelial cell polarity. Orthologous to human FRMD4A (FERM domain containing 4A) and FRMD4B (FERM domain containing 4B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F07C6.4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
19
Sequence:
Chromosome: IV; NC_003282.8 (12805925..12830115)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene LIM domain-containing protein pin-2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Bax inhibitor-1 family protein Neighboring gene TLC domain-containing protein Neighboring gene transcellular chaperone signaling (x)cross tissue

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in establishment of epithelial cell polarity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cytohesin Ubiquitin Protein Inducing domain-containing protein;FERM domain-containing protein
NP_001255674.1
  • Confirmed by transcript evidence
NP_001293862.1
  • Confirmed by transcript evidence
NP_001293863.1
  • Confirmed by transcript evidence
NP_001293864.1
  • Confirmed by transcript evidence
NP_001370283.1
  • Confirmed by transcript evidence
NP_001379112.1
  • Confirmed by transcript evidence
NP_502441.2
  • Confirmed by transcript evidence
NP_502442.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12805925..12830115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001306933.4 → NP_001293862.1  FERM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293862.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061ACE0
    Conserved Domains (4) summary
    smart00295
    Location:18 → 219
    B41; Band 4.1 homologues
    pfam11029
    Location:829 → 906
    DAZAP2; DAZ associated protein 2 (DAZAP2)
    pfam11819
    Location:416 → 565
    DUF3338; Domain of unknown function (DUF3338)
    cl17171
    Location:215 → 360
    PH-like; Pleckstrin homology-like domain

  2. NM_001383224.2 → NP_001370283.1  FERM domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EGL0
    Conserved Domains (3) summary
    smart00295
    Location:18 → 219
    B41; Band 4.1 homologues
    pfam11819
    Location:411 → 565
    DUF3338; Domain of unknown function (DUF3338)
    cl17171
    Location:215 → 360
    PH-like; Pleckstrin homology-like domain

  3. NM_001268745.3 → NP_001255674.1  FERM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255674.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECW4
    Conserved Domains (4) summary
    smart00295
    Location:18 → 219
    B41; Band 4.1 homologues
    cd13191
    Location:215 → 360
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    pfam11029
    Location:900 → 977
    DAZAP2; DAZ associated protein 2 (DAZAP2)
    pfam11819
    Location:416 → 565
    DUF3338; Domain of unknown function (DUF3338)

  4. NM_070040.8 → NP_502441.2  FERM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502441.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8I093
    Conserved Domains (2) summary
    smart00295
    Location:18 → 219
    B41; Band 4.1 homologues
    cl17171
    Location:215 → 359
    PH-like; Pleckstrin homology-like domain

  5. NM_001306934.3 → NP_001293863.1  FERM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293863.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061AIT4
    Conserved Domains (3) summary
    pfam11819
    Location:253 → 402
    DUF3338; Domain of unknown function (DUF3338)
    cl09511
    Location:6 → 56
    FERM_B-lobe; FERM domain B-lobe
    cl17171
    Location:52 → 197
    PH-like; Pleckstrin homology-like domain

  6. NM_001306935.3 → NP_001293864.1  FERM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293864.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061AKJ3
    Conserved Domains (4) summary
    pfam11029
    Location:666 → 743
    DAZAP2; DAZ associated protein 2 (DAZAP2)
    pfam11819
    Location:253 → 402
    DUF3338; Domain of unknown function (DUF3338)
    cl09511
    Location:6 → 56
    FERM_B-lobe; FERM domain B-lobe
    cl17171
    Location:52 → 197
    PH-like; Pleckstrin homology-like domain

  7. NM_070041.7 → NP_502442.2  Cytohesin Ubiquitin Protein Inducing domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502442.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECX1
    Conserved Domains (1) summary
    pfam11819
    Location:78 → 227
    DUF3338; Domain of unknown function (DUF3338)

  8. NM_001392420.1 → NP_001379112.1  Cytohesin Ubiquitin Protein Inducing domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECS7
    Conserved Domains (1) summary
    pfam11819
    Location:5 → 159
    DUF3338; Domain of unknown function (DUF3338)
Nucleotide Protein
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