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rps-23 Small ribosomal subunit protein uS12 [ Caenorhabditis elegans ]

Gene ID: 178188, updated on 2-Nov-2024

Summary

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Official Symbol
rps-23
Official Full Name
Small ribosomal subunit protein uS12
Primary source
WormBase:WBGene00004492
Locus tag
CELE_F28D1.7
See related
AllianceGenome:WB:WBGene00004492
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in cytosol and rough endoplasmic reticulum. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in ribosome. Is expressed in several structures, including anal depressor muscle; excretory cell; intestine; nervous system; and pharynx. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rps-23 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (12390298..12391053, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ig-like domain-containing protein Neighboring gene ncRNA Neighboring gene putative dolichol-phosphate mannosyltransferase subunit 3 Neighboring gene Long-chain-fatty-acid--CoA ligase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Increased fidelity of protein synthesis extends lifespan. Martinez-Miguel VE, et al. Cell Metab, 2021 Nov 2. PMID 34525330, Free PMC Article
  2. Isolation of eight novel Caenorhabditis elegans small RNAs. Wachi M, et al. Gene, 2004 Jun 23. PMID 15194189
  3. The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans. Davis DE, et al. Genetics, 2009 Aug. PMID 19448268, Free PMC Article
  4. Regulation of the C. elegans molt by pqn-47. Russel S, et al. Dev Biol, 2011 Dec 15. PMID 21989027, Free PMC Article
  5. Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1. Fuhrman LE, et al. PLoS Genet, 2009 Sep. PMID 19763173, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
located_in rough endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Small ribosomal subunit protein uS12
NP_502365.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12390298..12391053 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069964.9 → NP_502365.1  Small ribosomal subunit protein uS12 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502365.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q19877
    Conserved Domains (1) summary
    PTZ00067
    Location:1 → 143
    PTZ00067; 40S ribosomal S23; Provisional

RNA

  1. NR_131618.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q19877.1

Gene LinkOut

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