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prx-14 Peroxisomal membrane protein PEX14 [ Caenorhabditis elegans ]

Gene ID: 178026, updated on 4-Jan-2025

Summary

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Official Symbol
prx-14
Official Full Name
Peroxisomal membrane protein PEX14
Primary source
WormBase:WBGene00004199
Locus tag
CELE_R07H5.1
See related
AllianceGenome:WB:WBGene00004199
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein import into peroxisome matrix, docking. Predicted to be located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 13A. Orthologous to human PEX14 (peroxisomal biogenesis factor 14). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See prx-14 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (11183132..11184310)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene RAP homolog (vertebrate Rap GTPase family) Neighboring gene Uncharacterized protein Neighboring gene Calponin-homology (CH) domain-containing protein;Choline/carnitine acyltransferase domain-containing protein Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Neighboring gene SKN-1 Dependent Zygotic transcript Neighboring gene F-box associated domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5. Kong J, et al. Nat Commun, 2020 Jan 29. PMID 31996685, Free PMC Article
  2. Molecular definitions of autophagy and related processes. Galluzzi L, et al. EMBO J, 2017 Jul 3. PMID 28596378, Free PMC Article
  3. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in protein import into peroxisome matrix, docking IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Peroxisomal membrane protein PEX14
NP_502097.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    11183132..11184310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069696.5 → NP_502097.1  Peroxisomal membrane protein PEX14 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502097.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93930
    Conserved Domains (1) summary
    pfam04695
    Location:10 → 58
    Pex14_N; Peroxisomal membrane anchor protein (Pex14p) conserved region
Nucleotide Protein
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Gene LinkOut

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