C08F8.2 ATP-dependent RNA helicase SUV3 homolog, mitochondrial [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: C08F8.2
Official Full Name: ATP-dependent RNA helicase SUV3 homolog, mitochondrial
Primary source: WormBase:WBGene00007444
Locus tag: CELE_C08F8.2
See related: AllianceGenome:WB:WBGene00007444
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable DNA binding activity; DNA helicase activity; and RNA helicase activity. Predicted to be involved in DNA duplex unwinding and mitochondrial RNA 3'-end processing. Predicted to be located in mitochondrial matrix. Predicted to be part of mitochondrial degradosome. Orthologous to human SUPV3L1 (Suv3 like RNA helicase). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See C08F8.2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 13

Sequence:: Chromosome: IV; NC_003282.8 (11150997..11154334)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

C08F8.2 (e-PCR)
- UniSTS:309010

F01G4.6 (e-PCR)
- UniSTS:321332

C08F8.1 (e-PCR)
- UniSTS:315458

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables DNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables DNA helicase activity	ISS Inferred from Sequence or Structural Similarity more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on acid anhydrides	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA duplex unwinding	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial RNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of mitochondrial degradosome	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
located_in mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: ATP-dependent RNA helicase SUV3 homolog, mitochondrial

NP_001040912.1

Confirmed by transcript evidence

NP_001255542.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

11150997..11154334

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001047447.5 → NP_001040912.1 ATP-dependent RNA helicase SUV3 homolog, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001040912.1

Status: REVIEWED

UniProtKB/Swiss-Prot

E9P872, Q17828, Q2XN00

Conserved Domains (5) summary

cd18805
Location:336 → 465

SF2_C_suv3; C-terminal helicase domain of ATP-dependent RNA helicase

cd17913
Location:187 → 332

DEXQc_Suv3; DEXQ-box helicase domain of Suv3

pfam12513
Location:606 → 649

SUV3_C; Mitochondrial degradasome RNA helicase subunit C terminal

pfam18114
Location:49 → 166

Suv3_N; Suv3 helical N-terminal domain

pfam18147
Location:536 → 576

Suv3_C_1; Suv3 C-terminal domain 1
NM_001268613.3 → NP_001255542.1 ATP-dependent RNA helicase SUV3 homolog, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255542.1

Status: REVIEWED

UniProtKB/TrEMBL

E9P872

Conserved Domains (4) summary

cd18805
Location:55 → 184

SF2_C_suv3; C-terminal helicase domain of ATP-dependent RNA helicase

pfam18147
Location:255 → 295

Suv3_C_1; Suv3 C-terminal domain 1

pfam12513
Location:325 → 368

SUV3_C; Mitochondrial degradasome RNA helicase subunit C terminal

cl28899
Location:1 → 51

DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily