F25H8.2 H/ACA ribonucleoprotein complex non-core subunit NAF1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F25H8.2
Official Full Name: H/ACA ribonucleoprotein complex non-core subunit NAF1
Primary source: WormBase:WBGene00009132
Locus tag: CELE_F25H8.2
See related: AllianceGenome:WB:WBGene00009132
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be involved in box H/ACA snoRNP assembly and ribosome biogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human NAF1 (nuclear assembly factor 1 ribonucleoprotein). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F25H8.2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 6

Sequence:: Chromosome: IV; NC_003282.8 (9932235..9933879)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F25H8.2 (e-PCR)
- UniSTS:306204

F25H8.1 (e-PCR)
- UniSTS:309945

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in box H/ACA snoRNP assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in box H/ACA snoRNP assembly	IEA Inferred from Electronic Annotation more info
involved_in pseudouridine synthesis	IEA Inferred from Electronic Annotation more info
involved_in ribosome biogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of sno(s)RNA-containing ribonucleoprotein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of sno(s)RNA-containing ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: H/ACA ribonucleoprotein complex non-core subunit NAF1

NP_501790.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

9932235..9933879

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069389.6 → NP_501790.1 H/ACA ribonucleoprotein complex non-core subunit NAF1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501790.1

Status: REVIEWED

UniProtKB/TrEMBL

Q19788

Conserved Domains (1) summary

pfam04410
Location:149 → 306

Gar1; Gar1/Naf1 RNA binding region