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msp-77 Major sperm protein 77/79 [ Caenorhabditis elegans ]

Gene ID: 177844, updated on 2-Nov-2024

Summary

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Official Symbol
msp-77
Official Full Name
Major sperm protein 77/79
Primary source
WormBase:WBGene00003464
Locus tag
CELE_F32B6.6
See related
AllianceGenome:WB:WBGene00003464
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in oocyte maturation; positive regulation of MAPK cascade; and positive regulation of smooth muscle contraction. Predicted to be located in cytoplasm; cytoskeleton; and pseudopodium. Is expressed in gonad; oocyte; and sperm. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See msp-77 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_003282.8 (9894631..9895014)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene SH2 domain-containing protein Neighboring gene Sperm-Specific family, class S Neighboring gene Sperm-specific class P protein 32 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A sperm cytoskeletal protein that signals oocyte meiotic maturation and ovulation. Miller MA, et al. Science, 2001 Mar 16. PMID 11251118
  2. Evidence for phosphorylation in the MSP cytoskeletal filaments of amoeboid spermatozoa. Fraire-Zamora JJ, et al. Int J Biochem Mol Biol, 2011. PMID 22003439, Free PMC Article
  3. Proteasomal ubiquitin receptor RPN-10 controls sex determination in Caenorhabditis elegans. Shimada M, et al. Mol Biol Cell, 2006 Dec. PMID 17050737, Free PMC Article
  4. Genomic organization of major sperm protein genes and pseudogenes in the nematode Caenorhabditis elegans. Ward S, et al. J Mol Biol, 1988 Jan 5. PMID 3351915
  5. Clustered organization of reproductive genes in the C. elegans genome. Miller MA, et al. Curr Biol, 2004 Jul 27. PMID 15268860

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in oocyte maturation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of MAPK cascade IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of smooth muscle contraction IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in pseudopodium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Major sperm protein 77/79
NP_501781.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9894631..9895014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069380.5 → NP_501781.1  Major sperm protein 77/79 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501781.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9TVW5
    Conserved Domains (1) summary
    pfam00635
    Location:9 → 114
    Motile_Sperm; MSP (Major sperm protein) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TVW5.3

Gene LinkOut

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Molecular Biology Databases
Research Materials