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lpl-1 Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial [ Caenorhabditis elegans ]

Gene ID: 177729, updated on 2-Nov-2024

Summary

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Official Symbol
lpl-1
Official Full Name
Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
Primary source
WormBase:WBGene00003066
Locus tag
CELE_ZC410.7
See related
AllianceGenome:WB:WBGene00003066
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lipoyl(octanoyl) transferase activity. Predicted to be involved in protein lipoylation. Predicted to be active in mitochondrion. Orthologous to human LIPT2 (lipoyl(octanoyl) transferase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lpl-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (9092173..9094032, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Potassium channel domain-containing protein Neighboring gene Transmembrane protein Neighboring gene Large ribosomal subunit protein mL42 Neighboring gene Methylosome subunit pICln Neighboring gene 4F5 domain-containing protein;Small EDRK-rich factor-like N-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Defining Caenorhabditis elegans as a model system to investigate lipoic acid metabolism. Lavatelli A, et al. J Biol Chem, 2020 Oct 30. PMID 32843480, Free PMC Article
  2. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables lipoyl(octanoyl) transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipoyl(octanoyl) transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein lipoylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial
NP_001335548.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    9092173..9094032 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001348646.5 → NP_001335548.1  Octanoyl-[acyl-carrier-protein]:protein N-octanoyltransferase LIPT2, mitochondrial [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1N7SYX2
    Conserved Domains (1) summary
    cd16444
    Location:16 → 226
    LipB; lipoyl/octanoyl transferase
Nucleotide Protein
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