U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

unc-24 Band 7 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177594, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
unc-24
Official Full Name
Band 7 domain-containing protein
Primary source
WormBase:WBGene00006761
Locus tag
CELE_F57H12.2
See related
AllianceGenome:WB:WBGene00006761
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human STOML1 (stomatin like 1). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See unc-24 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (7979870..7982011)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene DUF148 domain-containing protein Neighboring gene Onchocerca Related Antigen family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ADP-ribosylation factor Neighboring gene Alpha-tubulin N-acetyltransferase 1;N-acetyltransferase domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A stomatin and a degenerin interact in lipid rafts of the nervous system of Caenorhabditis elegans. Sedensky MM, et al. Am J Physiol Cell Physiol, 2004 Aug. PMID 15102610
  2. The alpha and beta subunits of nematode actin capping protein function in yeast. Waddle JA, et al. Mol Biol Cell, 1993 Sep. PMID 8257793, Free PMC Article
  3. Understanding anesthesia: making genetic sense of the absence of senses. Humphrey JA, et al. Hum Mol Genet, 2002 May 15. PMID 12015284
  4. Dominant unc-37 mutations suppress the movement defect of a homeodomain mutation in unc-4, a neural specificity gene in Caenorhabditis elegans. Miller DM 3rd, et al. Genetics, 1993 Nov. PMID 7904971, Free PMC Article
  5. MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain. Zhang S, et al. Curr Biol, 2004 Nov 9. PMID 15530389

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. unc-1, unc-24, and ssu-1 are neuronal stomatin-like proteins sharing regulatory roles with a sulfotransferase enzyme
    Title: Sulfated signal from ASJ sensory neurons modulates stomatin-dependent coordination in Caenorhabditis elegans.
  2. Mutations in the unc-24 gene alter the distribution of UNC-1 in lipid rafts
    Title: A stomatin and a degenerin interact in lipid rafts of the nervous system of Caenorhabditis elegans.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Band 7 domain-containing protein
NP_001355386.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7979870..7982011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001368443.4 → NP_001355386.1  Band 7 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ED76, Q7KPQ9
    Conserved Domains (2) summary
    pfam02036
    Location:338 → 437
    SCP2; SCP-2 sterol transfer family
    cl19107
    Location:146 → 263
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools