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F57H12.5 Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177592, updated on 2-Nov-2024

Summary

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Official Symbol
F57H12.5
Official Full Name
Tyrosine-protein phosphatase domain-containing protein
Primary source
WormBase:WBGene00019020
Locus tag
CELE_F57H12.5
See related
AllianceGenome:WB:WBGene00019020
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F57H12.5 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (7967306..7969600)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PCI domain-containing protein Neighboring gene Homeobox protein ceh-19 Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Piwi domain-containing protein Neighboring gene DUF148 domain-containing protein Neighboring gene Onchocerca Related Antigen family

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tyrosine-protein phosphatase domain-containing protein
NP_001294193.1
  • Confirmed by transcript evidence
NP_501331.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7967306..7969600
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068930.5 → NP_501331.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501331.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45095
    Conserved Domains (2) summary
    smart00194
    Location:220 → 500
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cl21483
    Location:255 → 498
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  2. NM_001307264.2 → NP_001294193.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294193.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    W6SBI6
    Conserved Domains (2) summary
    smart00194
    Location:220 → 477
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cl21483
    Location:255 → 475
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

RNA

  1. NR_131579.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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