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flp-13 SPSAVPLIRF-amide [ Caenorhabditis elegans ]

Gene ID: 177547, updated on 9-Dec-2024

Summary

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Official Symbol
flp-13
Official Full Name
SPSAVPLIRF-amide
Primary source
WormBase:WBGene00001456
Locus tag
CELE_F33D4.3
See related
AllianceGenome:WB:WBGene00001456
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway; regulation of cellular response to heat; and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in extracellular region. Is expressed in nerve ring; neurons; and spicule protractor muscle. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See flp-13 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (7696932..7698420, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Inositol 1,4,5-trisphosphate receptor itr-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Putative sphingolipid delta(4)-desaturase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-throughput, motility-based sorter for microswimmers such as C. elegans. Yuan J, et al. Lab Chip, 2015 Jul 7. PMID 26008643, Free PMC Article
  2. FMRFamide-like FLP-13 neuropeptides promote quiescence following heat stress in Caenorhabditis elegans. Nelson MD, et al. Curr Biol, 2014 Oct 20. PMID 25264253, Free PMC Article
  3. The RFamide receptor DMSR-1 regulates stress-induced sleep in C. elegans. Iannacone MJ, et al. Elife, 2017 Jan 17. PMID 28094002, Free PMC Article
  4. FRPR-4 Is a G-Protein Coupled Neuropeptide Receptor That Regulates Behavioral Quiescence and Posture in Caenorhabditis elegans. Nelson MD, et al. PLoS One, 2015. PMID 26571132, Free PMC Article
  5. Isolation and preliminary biological assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans. Marks NJ, et al. Biochem Biophys Res Commun, 2001 Sep 7. PMID 11527423

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables neuropeptide receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuropeptide signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cellular response to heat IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of circadian sleep/wake cycle, sleep IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IC
Inferred by Curator
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SPSAVPLIRF-amide
NP_501255.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7696932..7698420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068854.5 → NP_501255.1  SPSAVPLIRF-amide [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501255.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O44185
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O44185.1

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