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afmd-1 BD-FAE-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177499, updated on 4-Jan-2025

Summary

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Official Symbol
afmd-1
Official Full Name
BD-FAE-like domain-containing protein
Primary source
WormBase:WBGene00017051
Locus tag
CELE_D2024.2
See related
AllianceGenome:WB:WBGene00017051
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in tryptophan catabolic process to kynurenine. Predicted to be active in cytoplasm. Orthologous to human AFMID (arylformamidase). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See afmd-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (7244228..7245502)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Putative fatty acid elongase 3 Neighboring gene ncRNA Neighboring gene Glutathione s-transferase kappa 2 Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans. Choi HS, et al. Nat Commun, 2023 Feb 2. PMID 36732543, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in tryptophan catabolic process to kynurenine IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BD-FAE-like domain-containing protein
NP_501149.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7244228..7245502
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068748.6 → NP_501149.1  BD-FAE-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501149.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18974
    Conserved Domains (1) summary
    COG0657
    Location:26 → 169
    Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
Nucleotide Protein
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