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C11D2.7 PUA domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177377, updated on 9-Dec-2024

Summary

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Official Symbol
C11D2.7
Official Full Name
PUA domain-containing protein
Primary source
WormBase:WBGene00015703
Locus tag
CELE_C11D2.7
See related
AllianceGenome:WB:WBGene00015703
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable RNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to several human genes including MCTS2 (MCTS family member 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C11D2.7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (6154558..6155396, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene BLOC-1-related complex subunit 5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Queuosine 5'-phosphate N-glycosylase/hydrolase Neighboring gene Ion transport domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
PUA domain-containing protein
NP_741412.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    6154558..6155396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171351.4 → NP_741412.1  PUA domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741412.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MXH7
    Conserved Domains (2) summary
    cd11609
    Location:4 → 81
    MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
    COG2016
    Location:18 → 177
    Tma20; Predicted ribosome-associated RNA-binding protein Tma20, contains PUA domain [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
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