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blos-7 BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177119, updated on 2-Nov-2024

Summary

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Official Symbol
blos-7
Official Full Name
BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein
Primary source
WormBase:WBGene00021376
Locus tag
CELE_Y37E11B.3
See related
AllianceGenome:WB:WBGene00021376
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Orthologous to human BORCS6 (BLOC-1 related complex subunit 6). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See blos-7 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
3
Sequence:
Chromosome: IV; NC_003282.8 (3580970..3582906, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene OToPetrin-Like;Otopetrin-1;Otopetrin-2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Enhancer of polycomb homolog 1-like Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene Transcription initiation factor TFIID subunit 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8. Niwa S, et al. Curr Biol, 2017 Sep 11. PMID 28823680, Free PMC Article
  2. A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes. Fazeli G, et al. Curr Biol, 2023 Feb 27. PMID 36652947, Free PMC Article
  3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in lysosome localization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of BORC complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein
NP_001368345.1
  • Confirmed by transcript evidence
NP_500377.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    3580970..3582906 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067976.5 → NP_500377.1  BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_500377.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9TYN4
    Conserved Domains (1) summary
    pfam10157
    Location:22 → 151
    DUF2365; Uncharacterized conserved protein (DUF2365)

  2. NM_001380153.1 → NP_001368345.1  BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PN06
    Conserved Domains (1) summary
    pfam10157
    Location:1 → 67
    BORCS6; BLOC-1-related complex sub-unit 6
Nucleotide Protein
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