fnta-1 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: fnta-1
Official Full Name: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Primary source: WormBase:WBGene00019823
Locus tag: CELE_R02D3.5
See related: AllianceGenome:WB:WBGene00019823
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Enables protein farnesyltransferase activity. Predicted to be involved in peptide pheromone maturation. Predicted to be part of CAAX-protein geranylgeranyltransferase complex and protein farnesyltransferase complex. Predicted to be active in cytoplasm. Orthologous to human FNTA (farnesyltransferase, CAAX box, subunit alpha). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See fnta-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 4

Sequence:: Chromosome: IV; NC_003282.8 (237591..240307, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R02D3.5 (e-PCR)
- UniSTS:319541

R02D3.2 (e-PCR)
- UniSTS:306367

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
contributes_to CAAX-protein geranylgeranyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables prenyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein farnesyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein prenyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptide pheromone maturation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein prenylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CAAX-protein geranylgeranyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of protein farnesyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

NP_001380029.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

237591..240307 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001392242.1 → NP_001380029.1 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

O44501

Conserved Domains (1) summary

PLN02789
Location:17 → 315

PLN02789; farnesyltranstransferase