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osm-7 Uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 176790, updated on 4-Jan-2025

Summary

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Official Symbol
osm-7
Official Full Name
Uncharacterized protein
Primary source
WormBase:WBGene00003887
Locus tag
CELE_T05D4.4
See related
AllianceGenome:WB:WBGene00003887
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable Notch binding activity. Involved in regulation of gene expression and response to osmotic stress. Predicted to be active in extracellular space. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See osm-7 in Genome Data Viewer
Location:
chromosome: III
Exon count:
12
Sequence:
Chromosome: III; NC_003281.10 (13576182..13580662)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein PNS1 Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extracellular proteins OSM-7 and OSM-8 are required for stress response gene regulation at all post-embryonic stages. Rodriguez Mendoza V, et al. MicroPubl Biol, 2022. PMID 36606078, Free PMC Article
  2. Dicarbonyl/L-xylulose reductase (DCXR) producing xylitol regulates egg retention through osmolality control in Caenorhabditis elegans. Kim YN, et al. Anim Cells Syst (Seoul), 2022. PMID 36275448, Free PMC Article
  3. An extracellular matrix damage sensor signals through membrane-associated kinase DRL-1 to mediate cytoprotective responses in Caenorhabditis elegans. Wimberly K, et al. Genetics, 2022 Mar 3. PMID 34849856, Free PMC Article
  4. Genetic and physiological activation of osmosensitive gene expression mimics transcriptional signatures of pathogen infection in C. elegans. Rohlfing AK, et al. PLoS One, 2010 Feb 2. PMID 20126308, Free PMC Article
  5. OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. Komatsu H, et al. PLoS Biol, 2008 Aug 12. PMID 18700817, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables Notch binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Uncharacterized protein
NP_001255209.1
  • Confirmed by transcript evidence
NP_001255210.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    13576182..13580662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268280.3 → NP_001255209.1  Uncharacterized protein CELE_T05D4.4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255209.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O45750

  2. NM_001268281.3 → NP_001255210.1  Uncharacterized protein CELE_T05D4.4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255210.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C8JQS1
Nucleotide Protein
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