U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

scav-2 SCAVenger receptor (CD36 family) related [ Caenorhabditis elegans ]

Gene ID: 176787, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
scav-2
Official Full Name
SCAVenger receptor (CD36 family) related
Primary source
WormBase:WBGene00013578
Locus tag
CELE_Y76A2B.6
See related
AllianceGenome:WB:WBGene00013578
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable scavenger receptor activity. Predicted to be involved in vesicle-mediated transport. Predicted to be active in membrane. Is expressed in reproductive system. Human ortholog(s) of this gene implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; progressive myoclonus epilepsy 4; and pulmonary tuberculosis. Orthologous to several human genes including SCARB1 (scavenger receptor class B member 1). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See scav-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (13550601..13555334, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial Neighboring gene F-box associated domain-containing protein Neighboring gene Fructose-bisphosphate aldolase 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. Means TK, et al. J Exp Med, 2009 Mar 16. PMID 19237602, Free PMC Article
  2. SCAV-3 affects apoptotic cell degradation in Caenorhabditis elegans. Ma A, et al. FEBS Open Bio, 2023 May. PMID 36947094, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables scavenger receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
SCAVenger receptor (CD36 family) related
NP_499802.3
  • Confirmed by transcript evidence;
    Product from WormBase gene class scav

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    13550601..13555334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067401.7 → NP_499802.3  SCAVenger receptor (CD36 family) related [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499802.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBM7
    Conserved Domains (1) summary
    pfam01130
    Location:46 → 505
    CD36; CD36 family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous