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rbm-7 RRM domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176710, updated on 9-Dec-2024

Summary

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Official Symbol
rbm-7
Official Full Name
RRM domain-containing protein
Primary source
WormBase:WBGene00012558
Locus tag
CELE_Y37D8A.21
See related
AllianceGenome:WB:WBGene00012558
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable single-stranded RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to several human genes including RBM7 (RNA binding motif protein 7). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rbm-7 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (12928370..12931867, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Transmembrane protein 33;Transmembrane protein 33 homolog Neighboring gene Small ribosomal subunit protein uS10m Neighboring gene Secreted protein Neighboring gene Ectopic P granules protein 3;Transmembrane protein 49 Neighboring gene Glutamate decarboxylase;Glutamate decarboxylase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RRM domain-containing protein
NP_499686.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    12928370..12931867 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067285.7 → NP_499686.2  RRM domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499686.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XWV4
    Conserved Domains (1) summary
    cl17169
    Location:12 → 85
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein
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