U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gex-4 GPN-loop GTPase 3 [ Caenorhabditis elegans ]

Gene ID: 176649, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
gex-4
Official Full Name
GPN-loop GTPase 3
Primary source
WormBase:WBGene00013550
Locus tag
CELE_Y75B8A.14
See related
AllianceGenome:WB:WBGene00013550
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTPase activity. Orthologous to human GPN3 (GPN-loop GTPase 3). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gex-4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (12216779..12218634, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene titin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Golgi pH regulator Neighboring gene Geminin homolog Neighboring gene Clathrin light chain

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Identification of potential interaction networks using sequence-based searches for conserved protein-protein interactions or "interologs". Matthews LR, et al. Genome Res, 2001 Dec. PMID 11731503, Free PMC Article
  2. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
  3. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
GPN-loop GTPase 3
NP_499587.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    12216779..12218634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067186.4 → NP_499587.1  GPN-loop GTPase 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499587.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XW68
    Conserved Domains (2) summary
    COG1100
    Location:2 → 203
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:7 → 252
    ATP_bind_1; Conserved hypothetical ATP binding protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools