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smap-1 Arf-GAP domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 176499, updated on 23-Jan-2025

Summary

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Official Symbol
smap-1
Official Full Name
Arf-GAP domain-containing protein
Primary source
WormBase:WBGene00012359
Locus tag
CELE_W09D10.1
See related
AllianceGenome:WB:WBGene00012359
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable GTPase activator activity. Predicted to be active in cytoplasm. Orthologous to several human genes including SMAP1 (small ArfGAP 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See smap-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
4
Sequence:
Chromosome: III; NC_003281.10 (10736893..10739792, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Phospholipid-transporting ATPase Neighboring gene ncRNA Neighboring gene Protein FAM32A Neighboring gene Tubulin beta chain

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia. Wang S, et al. Front Cell Dev Biol, 2021. PMID 34901019, Free PMC Article
  2. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
  3. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  4. Automated profiling of gene function during embryonic development. Green RA, et al. Cell, 2024 Jun 6. PMID 38759650,
  5. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Arf-GAP domain-containing protein
NP_499364.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10736893..10739792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066963.8 → NP_499364.1  Arf-GAP domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499364.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O18181
    Conserved Domains (2) summary
    cd08839
    Location:20 → 122
    ArfGap_SMAP; Stromal membrane-associated proteins; a subfamily of the ArfGAP family
    pfam04625
    Location:301 → 415
    DEC-1_N; DEC-1 protein, N-terminal region
Nucleotide Protein
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